They will also face questions over Project Big Picture, as will Football Association chairman Greg Clarke, whose role in the proceedings has come under scrutiny.
“Covid has exposed many of the fissures in our society and this is one of the deepest and football has been exposed, frankly, as having the economics of the madhouse in many respects,” committee chair Julian Knight told BBC Sport.
He said there are concerns that 12 to 15 EFL clubs could go under as a result of the financial crisis caused by coronavirus, which has been worsened by the lack of fans.
The government has made clear it will not provide a bailout to elite football.
The Premier League’s offer of a £50m package for Leagues One and Two, made up of grants and loans, was rejected by the EFL in October. The EFL has a board meeting on Thursday, and Premier League clubs are also meeting.
Culture secretary Oliver Dowden said in the House of Commons on Thursday that sports minister Nigel Huddleston met with the Premier League and EFL this week to “reiterate the need to reach an agreement in the interests of all fans”, adding that he was “disappointed” with the current situation.
“We’ll be looking to see exactly what they are going to do in order to ensure that we don’t end up with a cataclysm in our national game,” added Knight.